Alterations in cardiac contractile proteins due to oxygen free radicals
نویسندگان
چکیده
منابع مشابه
Formation of peroxides in amino acids and proteins exposed to oxygen free radicals.
Dilute aqueous solutions of BSA or lysozyme gave positive tests for peroxides after exposure to reactive oxygen species. The reactive species were generated by gamma-irradiation, reduction of H2O2 with Fe2+ ions or thermal decomposition of an azo compound. Peroxides were assayed by an iodometric method. Identification of the new groups as hydroperoxides was confirmed by their ability to oxidize...
متن کاملOxygen-Derived Free Radicals in Rats
Myocardial ischemia and reperfusion can evoke excitation of cardiac vagal afferent nerve endings and activation of a cardiogenic depressor reflex (Bezold-Jarisch effect). We postulate that oxygen-derived free radicals, which are well known to be produced during prolonged ischemia and reperfusion, contribute to this excitation. Hydroxyl radicals derived from hydrogen peroxide (H202) activate abd...
متن کاملbiochemical, hematological and pathological alterations associated with ascites in broilers and the role of oxygen-derived free radicals
three hundred and fifteen day -old chickens were used to test the relationship between oxygen-derived free radicals and the biochemical, hematological and pathological alterations(associtd with ascites). they were randomly divided into three experimental groups and ascites were developed in two groups of animals by exposing them to low temperature or administration of triiodothyronine (t3,), an...
متن کاملSurgical stress-induced alterations in retinoid metabolism in the small intestine: role of oxygen free radicals.
Oxidative stress in the small intestine can result in altered cell proliferation, migration, and differentiation of villus-crypt cells. Retinoid metabolism is recognized as an important mediator of cellular differentiation in the intestine. This study examined the effect of oxidative stress in retinoid metabolism in a surgical stress model. Surgical stress was performed by handling the intestin...
متن کاملIntestinal mucosal alterations in experimental cirrhosis in the rat: role of oxygen free radicals.
Cirrhosis is associated with altered gastrointestinal function, and bacterial translocation from the gut plays an important role in the etiology of spontaneous bacterial peritonitis (SBP) seen in this condition. Although alterations in gut motility and intestinal permeability are recognized in cirrhosis, the intestinal damage at the cellular and subcellular levels is not well understood. This s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - General Subjects
سال: 1991
ISSN: 0304-4165
DOI: 10.1016/0304-4165(91)90045-i